What are IONPs?
IONPs interact with myeloid cells specialized in the capture of particulate materials, such as macrophages or dendritic cells. As IONPs circulate through the vascular system, they also encounter endothelial cells. Finally, IONP also affects the tumor microenvironment.
Are iron oxide nanoparticles toxic?
Iron oxide MNPs are the most preferable nanomaterials in medical sciences, due to their features of minimal toxicity, and excellent physiochemical properties such as superparamagnetism, stability in aqueous solutions and biocompatibility [9,11,12,13].
Is iron oxide safe for MRI?
The iron oxide inorganic core is small enough to produce a pronounced positive contrast in MRI, and the zwitterionic surface ligand, which was recently developed by Wei and coworkers in the Bawendi research group, makes the iron oxide particles water-soluble, compact, and biocompatible.
How is iron oxide formed?
Iron (III) oxide, or ferric oxide, is the product that is formed when iron undergoes oxidation. This can be prepared in the laboratory by electrolyzing a sodium bicarbonate solution, an inert electrolyte, with an iron anode. The resulting hydrated iron(III) oxide, is dehydrated at around 200 °C.
What is iron oxide made of?
Iron oxides are compounds that are basically composed of iron and oxygen.
Why is precession important in MRI?
The precessional path around the magnetic field is circular like a spinning top. The Larmor or precessional frequency in MRI refers to the rate of precession of the magnetic moment of the proton around the external magnetic field. The frequency of precession is related to the strength of the magnetic field, B0.
How are nanoporous iron oxide nanoparticles made?
Nanoporous iron oxide (Fe3O4) nanoparticles (NIONPs) have been widely used as promising agents in biomedical applications. Herein, the NIONPs were synthesized by one-step hydrothermal method and well-characterized by FESEM and TEM investigations.
Are iron oxide nanopartcles antibacterial?
Antibacterial activity of iron oxide nanopartcles The in vitro bactericidal study of the IONPs was performed against different pathogenic bacteria like Staphylococcus aureus, Proteus vulgaris and Pseudomonas aeruginosa following the method of well diffusion [ 29 ].
How does the morphology of the nano-material affect its properties?
It is well documented that the nature of morphology of the nano-material can have great impact on the electronic characteristics, magnetic behaviours, catalytic activities, therapeutic efficacy and so on [ 7, 8, 9, 10, 11, 12, 13, 14, 15, 16 ].