What is the cellular morphology of cholera?

What is the cellular morphology of cholera?

Vibrio cholerae, the pathogenic bacterium responsible for the diarrheal disease cholera, adopts a characteristic “comma”-shaped cell morphology.

What morphology does Vibrio cholera have?

V cholerae is a comma-shaped, gram-negative aerobic or facultatively anaerobic bacillus that varies in size from 1-3 µm in length by 0.5-0.8 µm in diameter (see the image below). Its antigenic structure consists of a flagellar H antigen and a somatic O antigen.

Which structure in cell causes cholera?

cholerae, which are distinguished based on the structure of a protein called the O antigen in the bacterium’s cell wall. Several of these serogroups are pathogenic in humans; however, only two serogroups of V. cholerae—O1 and O139 (sometimes called the Bengal serogroup)—are known to cause cholera.

What is the gram reaction and morphology of Vibrio cholerae?

CHARACTERISTICS: Vibrio cholerae is a gram negative, non-spore forming, curved rod that is oxidase positive(1,2,3). It is very motile and has a single polar flagellum(1). The bacterium is 1- 3 µm by 0.5-0.8 µm, is a facultative anaerobe and is part of the Vibronaceae family(1,3).

What is the shape of bacillus of Vibrio?

Due to the presence of a rigid cell wall, bacteria maintain a definite shape, though they vary as shape, size and structure. When viewed under light microscope, most bacteria appear in variations of three major shapes: the rod (bacillus), the sphere (coccus) and the spiral type (vibrio).

Does Vibrio cholerae have cell wall?

In the past decades, Vibrio cholerae, the gram-negative pathogen causing the diarrheal disease cholera, has become a major model for understanding cell wall genetics, biochemistry, and physiology. More than 100 articles have shed light on novel cell wall genetic determinants, regulatory links, and adaptive mechanisms.

What is the structure of cholera toxin?

The complete toxin is a hexamer made up of a single copy of the A subunit (part A, enzymatic, P01555), and five copies of the B subunit (part B, receptor binding, P01556), denoted as AB5. Subunit B binds while subunit A activates the G protein which activates adenylate cyclase.

What will be the shape of bacillus bacteria?

bacillus, (genus Bacillus), any of a genus of rod-shaped, gram-positive, aerobic or (under some conditions) anaerobic bacteria widely found in soil and water. The term bacillus has been applied in a general sense to all cylindrical or rodlike bacteria.

What is a characteristic of cholera?

Signs and symptoms of cholera dehydration include irritability, fatigue, sunken eyes, a dry mouth, extreme thirst, dry and shriveled skin that’s slow to bounce back when pinched into a fold, little or no urinating, low blood pressure, and an irregular heartbeat.

What is the shape of Vibrio bacteria?

vibrio, (genus Vibrio), any of a group of comma-shaped bacteria in the family Vibrionaceae.

How does cholera toxin enter cells?

Cholera toxin (CT), an AB5-subunit toxin, enters host cells by binding the ganglioside GM1 at the plasma membrane (PM) and travels retrograde through the trans-Golgi Network into the endoplasmic reticulum (ER).

What happens to the intestinal cells during cholera?

Cholera is caused by the bacteria Vibrio cholerae. These bacteria release a toxin that causes an increased amount of water to be released from cells that line the intestines. This increase in water produces severe diarrhea.

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