What are allelic variants?

Allelic variation describes the presence or number of different allele forms at a particular locus (locus or loci = place) on a chromosome (allelic variation is sometimes used more loosely to describe the overall diversity present).

What is the many variants of allelic forms of a gene?

When there is a gene existing in more than two allelic forms, this condition is referred to as multiple allelism. Allelism refers to any of the several forms of a gene. These genetic variations arise usually through mutation and therefore are responsible for hereditary variations.

What are genetic variants and haplotypes?

A haplotype is a physical grouping of genomic variants (or polymorphisms) that tend to be inherited together. A specific haplotype typically reflects a unique combination of variants that reside near each other on a chromosome.

What are monomorphic alleles?

If in the population only one allele occurs at a site or locus, we shall say that it is monomorphic, or monoallelic, in that population.

What are gene variants called?

A gene variant is a permanent change in the DNA sequence that makes up a gene. This type of genetic change used to be known as a gene mutation, but because changes in DNA do not always cause disease, it is thought that gene variant is a more accurate term.

Which example is a variant of a gene?

Genetic variation results in different forms, or alleles?, of genes. For example, if we look at eye colour, people with blue eyes have one allele of the gene for eye colour, whereas people with brown eyes will have a different allele of the gene.

What is a monomorphic variant?

In my understanding, monomorphic means something that appears in just one state (or form), in contrast to polymorphic that means something that appears in more than one form. SNPs are by definition polymorphic. A monomorphic site is one site in which all the individuals have the same form (genotype).

What is polymorphic variation?

Polymorphism, as related to genomics, refers to the presence of two or more variant forms of a specific DNA sequence that can occur among different individuals or populations. The most common type of polymorphism involves variation at a single nucleotide (also called a single-nucleotide polymorphism, or SNP).

What is variant allele frequency?

Variant allele frequency (VAF) VAF is the percentage of sequence reads observed matching a specific DNA variant divided by the overall coverage at that locus. Because NGS provides a near random sample, VAF is thus a surrogate measure of the proportion of DNA molecules in the original specimen carrying the variant.

What is monomorphic and polymorphic?

VT is considered sustained if it is continuous for at least 30 seconds. If the QRS complex has primarily a single morphology, the VT is monomorphic, whereas if the QRS complex varies, the VT is polymorphic.

What is the difference between monomorphic and pleomorphic?

What is the difference between monomorphic and pleomorphic bacteria? most bacteria are monomorphic, particularly in pure culture, they do not change shape. pleomorphic bacteria do not have cell wall and have varying shapes, seen in Mycoplasma pneumoniae and others.

What is difference between polymorphism and variation?

A mutation is defined as any change in a DNA sequence away from normal. This implies there is a normal allele that is prevalent in the population and that the mutation changes this to a rare and abnormal variant. In contrast, a polymorphism is a DNA sequence variation that is common in the population.