What functional groups are present in acetaminophen?
The functional groups in acetaminophen are phenol, aromatic ring, and amide.
Which reaction occurs in the synthesis of paracetamol from p-aminophenol?
Synthesis of Paracetamol (Morning) Paracetamol is made by reacting 4-aminophenol with ethanoic anhydride (more commonly called acetic anhydride). This reaction forms an amide bond and ethanoic acid as a by- product. When the reaction is complete the paracetamol is then isolated and purified.
What are the functional group present in 4-aminophenol?
4-aminophenol is an amino phenol (one of the three possible isomers) which has the single amino substituent located para to the phenolic -OH group.
What is the chemical structure of acetaminophen?
C8H9NO2Paracetamol / Formula
What functional groups are found in aspirin?
The common name of aspirin is acetylsalicylic acid and its IUPAC name is 2-Acetoxybenzoic acid. Between ester and carboxylic acid functional groups the highest priority functional group is carboxylic acid. Hence, in aspirin carboxylic acid is the principal functional group. Therefore, the correct option is B, -COOH.
Which functional group of 4-aminophenol is more reactive towards electrophiles?
In 4-aminophenol in alkaline medium phenolic OH is more reactive where as in Neutral medium NH2 is more reactive.
Is acetaminophen a 4-aminophenol derivative?
Acetaminophen is a p-aminophenol derivative with analgesic and antipyretic properties comparable to those of aspirin.
Which functional group in paracetamol is responsible for antipyretic action?
The antipyretic effect of paracetamol occurs independent of transient receptor potential ankyrin 1-mediated hypothermia and is associated with prostaglandin inhibition in the brain. Keywords: N-acetyl cysteine; NAPQI; TRPA1; acetaminophen; fever.
How many sp2 and sp3 hybridized carbons are in acetaminophen?
The molecule is planar with 7 carbon atoms with sp2 hybridization. Its chemical structure can be written as below, in the common representations used for organic molecules. Occurrence: Acetaminophen is not found in nature.
What functional group reacts with acetic anhydride to give the ester in production of aspirin?
To make acetylsalicylic acid, the -OH group of the salicylic acid reacts with acetic acid to produce the ester and water.
Which is more polar p-aminophenol or p nitrophenol?
p-aminophenol < p-chloro phenol < p-nitrophenol.
What is the example of para-aminophenol NSAID?
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) The para- aminophenol derivatives include acetaminophen, and the indole acetic acid derivatives include indomethacin and etodolac. The heteroarylacetic acid derivatives are typified by diclofenac. Arylpropionic acids include ibuprofen and naproxen.