What is the most effective aromatase inhibitor?

In an early report, exemestane was significantly better than tamoxifen in response rate and median time to progression, with overall survival data not yet available. To date, letrozole appears to be the most effective aromatase inhibitor in the first-line advanced breast cancer setting.

Is berberine an aromatase inhibitor?

The research involved testing a combination of treatment with berberine and fulvestrant, a clinically utilized estrogen receptor antagonist that the authors indicated also acts as an aromatase antagonist.

What is the weakest aromatase inhibitor?

Some doctors (mine, for example) feel that Arimidex, which is the “weakest” of the three, actually provides some added benefit by NOT suppressing as much aromatase. They feel that a tiny bit of estrogen in your body is better than none at all.

Does berberine reduce estrogen?

Also, our results showed that the administration of berberine caused a significant rise in FSH, and progesterone levels and a significant decrease in the levels of LH, estrogen, and testosterone.

Does grapeseed extract reduce estrogen?

800 mg dose daily for 12 weeks. Primary Outcome Measures : To document that grape seed extract taken orally will decrease plasma estrogen levels (estrone (E1), estradiol (E2), and E1-conjugates) and increase precursor androgen levels (testosterone and androstenedione) in healthy postmenopausal women.

Do aromatase inhibitors cause hair thinning?

Findings from this study suggest that aromatase inhibitor use is associated with an increased risk of hair loss and hair thinning independent of chemotherapy and age; these side effects are likely due to the substantial decrease in estrogen concentrations resulting from treatment with this drug.

Does berberine mess with hormones?

Also, our results showed that the administration of berberine caused a significant rise in FSH, and progesterone levels and a significant decrease in the levels of LH, estrogen, and testosterone. Our results showed that treatment with berberine regulates the level of sex hormones in the letrozole-induced PCOS rats.

Is berberine good for hormones?

One small study in 89 women with PCOS found that berberine was more effective at reducing both waist-to-hip ratio and male hormone levels than Metformin ( 12 ).

Does zinc stop estrogen?

Zinc supports the stress response. Inadequate or excess cortisol (the stress hormone) affects the production of estrogen and progesterone in women. Either too high or too low levels of estrogens can cause issues with menstruation, mood swings, early menopause, infertility and more. Zinc reduces inflammation.