What level is considered IgA deficient?
IgA deficiency is defined as a serum IgA concentration lower than 7 mg/dL, with normal serum levels of IgM and IgG. It is one of the most common B-cell immunodeficiencies, with an approximate incidence of 1 in 400 to 2000 individuals in the general population.
What does it mean when your immunoglobulin IgA is low?
Overview. Selective IgA deficiency is an immune system condition in which you lack or don’t have enough immunoglobulin A (IgA), a protein that fights infection (antibody). Most people with selective IgA deficiency don’t have recurrent infections.
How do I know if I am IgA deficiency?
How is selective IgA deficiency diagnosed? Immunologists, or doctors who specialize in the immune system, may send blood tests to evaluate a patient who with frequent infections or autoimmune disease. Low levels of IgA confirm the diagnosis of selective IgA deficiency.
How do you fix low IgA?
There is no cure for IgA deficiency. Immunotherapy does not work to treat it. Complications for IgA deficiency include asthma, diarrhea, ear and eye infections, autoimmune diseases, and pneumonia. You can limit the spread of germs and illnesses by washing your hands often and staying away from large crowds.
What should I do if I have IgA deficiency?
Most people with selective IgA deficiency don’t need treatment unless they have frequent infections. In some cases, treatment may include a long course of antibiotics to help prevent an infection from returning.
What drugs cause IgA deficiency?
Those cases of primary IgA deficiency that appear familial in nature have no common Mendelian pattern. Secondary IgA deficiency can result from a myriad of factors. Many drugs are causative agents for IgA deficiency, including, for example, cyclosporine, gold, penicillamine, and antiepileptics.
What level of IgA indicates celiac?
Intestinal biopsies In some circumstances, if upper GI endoscopy is not feasible, a reliable diagnosis of celiac disease can be made if the initial blood sample has a very strongly positive tTG-IgA result that is greater than 10 times the upper limit of normal, and a subsequent blood sample has a positive EMA-IgA.