Can drugs affect PSA levels?

Can drugs affect PSA levels?

The levels of prostate-specific antigen (PSA), a widely used prostate cancer marker, are influenced by a number of drugs, such as non-steroidal anti-inflammatory drugs and statins.

What drugs can raise PSA levels?

Official Answer

  • Nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin, ibuprofen and naproxen.
  • Cholesterol-lowering statins, such as Lipitor (atorvastatin) and Zocor (simvastatin)
  • High blood pressure drugs known as thiazide diuretics.

What does PSA mean in drugs?

A peptide vaccine containing the prostate specific antigen (PSA) with potential antineoplastic activity.

What can throw off a PSA test?

Semen released during sexual activity can cause PSA levels to rise temporarily, which may affect the test results. For the same reason, before having a PSA test men should not have: exercised vigorously in the previous 48 hours. an active urinary infection (PSA may remain raised for many months)

What causes a sudden spike in PSA?

Besides cancer, other conditions that can raise PSA levels include an enlarged prostate (also known as benign prostatic hyperplasia or BPH ) and an inflamed or infected prostate (prostatitis). Also, PSA levels normally increase with age.

What causes your PSA to go up and down?

While age and genetics both affect PSA levels, lifestyle factors actually play the largest role. That’s why simple changes to health, diet, and exercise routines can naturally bring down PSA levels.

What can cause elevated PSA?

High PSA? Here are 7 common things that can affect your PSA level

  • Age. Older men’s normal PSA levels run a little higher than those of younger men.
  • Prostate size.
  • Prostatitis.
  • Benign prostatic hyperplasia (BPH)
  • Urinary tract infection or irritation.
  • Prostate stimulation.
  • Medications.

Can anxiety raise PSA levels?

One hospital-based study found that higher anxiety increased PSA screening rates in men, particularly for those with a family history of PCa seeking reassurance from a normal test result.

What can cause a false high PSA reading?

What causes PSA to rise?

For example, the PSA level tends to increase with age, prostate gland size, and inflammation or infection. A recent prostate biopsy will also increase the PSA level, as can ejaculation or vigorous exercise (such as cycling) in the 2 days before testing.

What can cause a sudden rise in PSA?

What medications raise PSA levels?

5-alpha reductase inhibitors—dutasteride (Avodart) and finasteride (Proscar)—which can reduce PSA levels by about 50 percent in many men who take them.

  • Some herbal and dietary supplements
  • Aspirin
  • Statins
  • Thiazide diuretics
  • What supplements reduce PSA levels?


  • Green tea.
  • Lycopene.
  • Modified citrus pectin.
  • Pomegranate.
  • Selenium.
  • Soy.
  • Vitamin D.
  • Vitamin E.
  • Multicomponent therapies.
  • What drugs cause elevated PSA?

    Drugs that can skew a PSA test include: Finasteride and Dutasteride: Medications used to treat an enlarged prostate, also called benign prostatic hyperplasia (BPH), and its symptoms It’s important to let your healthcare provider know if you take or have started taking any of these medications before you get a PSA test.

    What are the reasons for elevated PSA levels?

    PSA velocity. PSA velocity is the change in PSA levels over time.

  • Percentage of free PSA. PSA circulates in the blood in two forms — either attached to certain blood proteins or unattached (free).
  • PSA density. Prostate cancers can produce more PSA per volume of tissue than benign prostate conditions can.
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