What percent of people have the ACTN3 gene?
Approximately 20%-30%
This variant form of the ACTN3 gene is very common in the general population. Approximately 20%-30% of the population (over 1 billion people worldwide) have two mutant genes (X/X genotype), and there is not any obvious effect on individuals who have either one or two copies of the variant gene.
What race has the ACTN3 gene?
Although these data suggest variation in the distribution of the ACTN3 R/X gene polymorphism across different populations, the present data demonstrate that most of the findings involved the Black and the Caucasian populations with limited evidence within Asian populations.
What does it mean if you have the ACTN3 gene?
What is the ACTN3 Gene? The ACTN3 gene is specifically found in fast-twitch (type II) muscle fibers, which are in charge of producing forceful muscle contraction that are especially needed for sprinting and weight-lifting. The gene produces a protein that regulates the function of these fibers.
What does the ACTN3 gene code for How does this impact athletic ability?
ACTN3 protein efficiency results in a higher proportion of fast-twitch muscle fibers, which allows fast muscle contractions for sprinting and high muscle strength. The most common polymorphism of the ACTN3 gene is R577X, a C-to-T base substitution of an arginine base (R) to a premature stop codon (X).
How do I know my genotype ACTN3?
Children can also give their blood samples to the nearest diagnostic center and find out which genes are responsible for their strength and endurance. By giving a unit of blood sample, a person can find out whether he is having ACTN3 protein in his muscles.
Do Jamaicans have speed genes?
The team has just begun to analyze the genetic data it has collected, but preliminary findings suggest that 70 percent of Jamaicans have the “strong” form of the ACTN3 gene—which produces a protein in their fast-twitch muscle fibers that has been linked to increased sprinting performance.
What is the elite athlete gene?
Studies have found that most elite power athletes have a specific genetic variant in a gene related to muscle composition called the ACTN3 gene. This variant causes muscle cells to produce alpha-actinin-3, a protein found in fast-twitch muscle fibers.
Can you test for ACTN3?
The test detects two genes ACE and ACTN3 connected with athletic performance.
Why are African runners faster?
The anthropometric literature shows that the center of mass in blacks is 3 percent higher above the ground than in whites. This means that blacks hold a 1.5 percent speed advantage in running, and whites hold a 1.5 percent speed advantage in swimming.
How do you tell if I have ACTN3?
Here’s how to check your ACTN3 gene: Check your genetic data for rs1815739 (23andMe v4, v5; AncestryDNA): C/C: functioning ACTN3, optimal for elite power athletes, more type IIx muscle fiber (RR) C/T: functioning ACTN3, optimal for elite power athletes (RX)
What type of mutation is ACTN3?
nonsense mutation
The alpha actinin 3 (ACTN3) gene is 16,489 base pairs and consists of 22 exons and 21 introns. ACTN3 has a single nucleotide polymorphism (SNP) that confers a nonsense mutation (C >T transition at nucleotide 1747, R557X) in exon 16 (see star) resulting in a truncated protein.
Why is Ethiopia so good at running?
Several factors have been proposed to explain the extraordinary success of the Kenyan and Ethiopian distance runners, including (1) genetic predisposition, (2) development of a high maximal oxygen uptake as a result of extensive walking and running at an early age, (3) relatively high hemoglobin and hematocrit, (4) …
